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Rl22 used to be one of my favorites, RL25 would work, as would 7828, 4831, Retumbo, H1000 or RL26/23. I’ve tried them all at one time or another. I like slow stuff in the 25-06 myself especially with 120’s.
What do you have available to you Dan?
4350 and Hunter have been the best performers for 115-120 grain bullets in the .25-06!IMR4350 is the powder I use in my brothers 25-06 with 117 and 120gr bullets.