My 30-378 got it's first kill since I got it, one of my bro's shot a nice 4X4 at 115 yds. Little bit way too much gun, but a clean kill. Buck was quartering away, bullet entered about halfway down the ribs, bout 4 or 5 inches back of the shoulder. Anyway, it was a a Speer HotCor 180 grain bullet with 111.5grns of Retumbo chasing it @3350fps because I didn't get a load developed in time for season. Not a great plan since Speer doesn't recommend those bullets for use over 3000fps. The entrance side had severe tissue damage, in a 6-8 inch radius of the wound, the front half of both lungs was missing, and Very surprisingly, the jacket of the bullet was caught in the muscle behind the shoulder blade on the other side. IT weighed 26.3grns. that is less than 15% weight retention. Not thrilled with that performance, but Speer doesn't recommend use at that velocity anyway. The result was great for Whitetail deer, but I'd still be tracking an elk.