I have taken a good number of animals with the AccuBond in .257 R, .308 Win, .300 WM and .338 WM. Have also been involved in the taking of others with the .375. These animals range from the size of warthogs to eland.
I have yet to see anything that could be considered bullet failure.
Beyond...
In a .270 WSM the BT, AB and NP will all work on deer. The AB will penetrate deeper than the BT and the NP deeper than the AB.
In the vitals I cannot imagine that you would see any difference. At longer ranges (less velocity) you should see more expansion from the BT and if you are one of...
You might consider the 1-4X Trijicon AccuPoint. I have used this scope extensively and the post reticle with the optional illuminated tip is very fast to pick up. I have one in 3-9X mounted on a 7.3 pound .416.