Welcome to the 280AI club. RL22 is my go to powder for 120-160 gr bullet weights. I have 16+ pounds so I am in good shape for some time. I had excellent accuracy with the 168 gr ABLR and IMR7828SSC.
The powders you are considering are all good choices. Of the three, I'd start with H4831SC.
JD338
I actually bought a few hundred Nosler 165 gr SB seconds last year and took a late season doe with one. That's the bullet I am actually going to hunt with in the 308.
I bought these Sierra's for plinking and banging steel because of the price point. Just too good a price to pass up.
JD338
I ran a few through the 308 this afternoon.
I used a proven load of IMR4064 and Ginex large rifle primers. Still shot just under MOA. Ran one through some jugs and found the jacket going into the 5th jug. The lead core was inside jug 5.
I also put two on the 200 yard gong. They landed just off...
Don't overlook the 45-70. It's a cartridge that's rich with history and can be loaded from mild to wild.
My little Marlin 1895G with a Leupold VX-3 1.75-6x32mm is a joy to carry and has taken deer for me as far as 160 yds. My best group with a Nosler 300 gr BST went .400" at 100 yds. Henry also...