Normally I would agree with JD. If you don't have access to Alliant powder, TU8000 seem to be much close to RL22 in burn rate, and it might be a better starting point for a rifle.
With a 10" barrel, the faster powder might work better. I was unable to locate any Vectan specific load data, but here is some Vihtavuori load data:
The Vectan NobelSport Handloading Manual #4 lists 70.2 grains of tu7000 as a maximum charge with 180 grain Spitzer soft point bullets for a velocity of 2940 fps and a pressure of 49110 psi. This is a small increase in charge weight over that found on the web.
I agree that this sounds low. However I'm reading the data from the Vectan Manual as recorded on the RCBS.Load data. It lists it as psi. It is interesting to note that 71.8 grains of tu8000 is listed as generating 49180 psi. In the 200 grain spitzer soft point, 73.8 grains of tu8000 is listed as generating 49800 psi. Even if this were CUP, it would be exceptionally low. The data for the 30-06 Springfield, shooting 180 grain RNSP bullets uses 54.3 grains of tu7000 to generate 13950 psi.
"The Vectan NobelSport Handloading Manual #4 lists 70.2 grains of tu7000 as a maximum charge with 180 grain Spitzer soft point bullets for a velocity of 2940 fps and a pressure of 49110 psi. This is a small increase in charge weight over that found on the web."
So for a Nosler 180 grs bullet (Boat tail) I put less powder ?
Use the data in the Vectan manual for the 180 grain spitzer. Reduce the maximum charge by 10 percent and work up in increments of 1 grain to ensure that you do not have a pressure issue.
Unfortunately, there is little use of Vectan powders in North America. Perhaps some of the European readers will be able to provide data. Have you tried communicating with the manufacturers of Vectan powders?