I admit to only trying two powders in the 338 Fed and the Barnes 160 TTSX. I first tried Alliant Power pro 2000MR which did extremely well in the .308 and 165 Swift AF bullet, for 2750fps ( 30.06 territory) but it only produced best accuracy with the 338 Fed/160 TTSX around 2750. Group was right at .75". However, TAC was the real "nitro", wonder powder! 52gr gave me 30007 or so average fps with every charge, from 50 to 52, being under .75". I am jazzed beyond adrenaline! ha. This really makes this little 338 Fed a step above the 30-06 in overall field use!