I'm thinking that done right, it could be a better seller than the big game rifles. Good idea!
Since some varmint shooters burn through a BUNCH of ammo with high velocity cartridges... Destroying barrels... It would be nice to have it setup for easy barrel swaps by the owner - similar to what can be done with a Savage rifle, or a McMillan built Tubb 2000. Pre-threaded, pre-chambered barrels are avail for those rifles, and it takes only a minimal amount of tools & expertise for the rifle owner to re-barrel...
+1 on the fast-twist .22-250 as well...
Am thinking the .204 Ruger or the 6mmBR necked to .20 cal, would be a great choice...