I have a mold for a 300 gr. semi-wadcutter but haven't been able to get it to shoot near point of am. Most loads I've trie shoot about 6" high at 25 yards. What I need to do is put a taller front sight on one of my .44 mags so the POI is at least closer to what I want. My mold for Elmer Keith's bullet actually casts out at 250 gr. but hits at point of aim and 25 yards.I have lots of experience loading the 44 mag in revolver...
Winchester 296 is king for me!
That said...240 gr work better than 225 and 300 gr are the best.
That was my experience in 4 different platforms... but your gun might be different but for me 300, nosler or hornady shot the best
good luck and enjoy!
Paul B.